Resumen |
Advances in micro and nanoengineering have permitted to
implement Organ-on-chips (OOC) that mimic accurately physiological
functions. OOC are multichannel 3D microfluidic cell culture biodevices
that mimic and model physiological mechanisms, activities,
functions and responses of organs and tissues. These biomimetic
microengineering approaches have gained significant relevance in
biomedicine because they allow providing a better approximation of
structure, behavior of cells and mechanisms of diseases to propose
better diagnostic methods and personalized therapies |